A pedigree of the family. III-2 represents the patient presented in this article. Three of her grandparents died of pancreatic cancer (I-3), Liver cancer (I-1) and breast cancer (I-2), respectively. Her father (II-4) was diagnosed with rhabdomyosarcoma at the age of 28. One of her uncle (II-2) was diagnosed with leukaemia at the age of 18. Her another uncle (II-3) developed lung cancer when he was 42 years old. Her two uncles have already died. Her mother (II-5) has not developed any types of tumor so far. But her aunt (II-6) has suffered from breast cancer since 56 years old. Her identical twin sister (III-3) developed breast cancer at 24 years of age. Square, male; circle, female. slash mark, deceased. Solid symbols represent cancer patients.