Table 1.
Group (N = 10) (Mean ± SD) | Body weight (gm; Initial) | Body weight (gm; Final) | Bladder weight (mg; Final) | Blood glucose (mg/dL; Initial) | Blood glucose (mg/dL; Final) |
---|---|---|---|---|---|
Control 4 w | 264.9 ± 9.5 | 300.9 ± 9.5 | 151.3 ± 32.2 | 138.7 ± 13.1 | 136.3 ± 8.9 |
DM 4 w | 257.1 ± 15.1 | 228.0 ± 9.0* | 267.5 ± 52.0* | 138.3 ± 10.0 | 426.1 ± 34.8* |
DM + hAFSCs 4 w | 260.7 ± 15.7 | 249.9 ± 28.1* | 260.8 ± 22.5* | 142.3 ± 15.9 | 410.1 ± 59.8* |
P value | 0.353 | <0.0001 | <0.0001 | 0.815 | <0.0001 |
Control 12 w | 260.3 ± 10.7 | 324.4 ± 22.1 | 166.5 ± 20.4 | 132.8 ± 12.9 | 144.3 ± 6.9 |
DM 12 w | 244.8 ± 15.6 | 233.9 ± 20.3* | 444.3 ± 80.4* | 135.1 ± 18.8 | 458.1 ± 63.1* |
DM + hAFSCs 12 w | 250.5 ± 13.4 | 259.8 ± 28.7* | 368.5 ± 55.2*† | 139.4 ± 18.6 | 381.1 ± 41.4*,‡ |
P value | 0.119 | <0.0001 | <0.0001 | 0.693 | <0.0001 |
†P < 0.05 vs. DM (12 w).
‡P < 0.001 vs. DM (12 w).
*P < 0.0001 vs. control (4 w and 12 w).
N = 10 rats in each group.
Initial body weight: body weight measured before sham treatment, STZ treatment or hAFSCs transplantation.
Final body weight: body weight measured 4 w and 12 w after sham treatment, STZ treatment or hAFSCs transplantation.
Final bladder weight: bladder weight measured 4 w and 12 w after sham treatment, STZ treatment or hAFSCs transplantation.