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. 2018 Feb 1;8:2076. doi: 10.1038/s41598-018-20273-9

Table 1.

Characteristics of the study population.

Variable All n (%) Dry eye group* n (%) Previous dry eye diagnosis n (%) Severe dry eye symptoms n (%)
Overall 3,107 (100) 398 (12.8) 317/3,107 (10.2) 151/3,107 (4.9)
Sex
Male 1067 (34.4) 105 (26.4) 71 (28.7) 34 (22.5)
Female 2032 (65.6) 293 (73.6) 176 (71.3) 117 (77.5)
Age category
18–39 1547 (50.3) 153 (38.9) 106 (43.5) 48 (32.2)
40–60 1052 (34.2) 139 (35.4) 86 (35.2) 52 (34.9)
60+ 474 (15.3) 101 (25.7) 52 (21.3) 49 (32.9)
Dryness symptom
Never 1224 (39.4) 12 (3.0) 12 (4.9)
Sometimes 1170 (37.7) 65 (16.3) 65 (26.3)
Often 531 (17.1) 161 (40.5) 161 (65.2)
Constantly 182 (5.9) 160 (40.2) 9 (3.6) 151 (100)
Irritation symptom
Never 631 (20.3) 10 (2.5) 10 (4.0)
Sometimes 1475 (47.5) 99 (24.9) 98 (39.7)
Often 751 (24.2) 167 (42.0) 121 (49.0) 47 (31.1)
Constantly 250 (8.0) 122 (30.7) 18 (7.3) 104 (68.9)
Frequency of risk factors
+60 years 474 (15.4) 101 (25.6) 52 (21.3) 49 (32.5)
≥40 years 1526 (49.5) 240 (60.8) 183 (58.3) 102 (67.5)
Diabetes 247 (7.9) 41 (10.3) 23 (9.3) 18 (11.9)
Menopause 294 (14.5) 70 (23.9) 35 (19.9) 35 (29.9)
Rheumatologic diseases 143 (4.6) 32 (8.0) 18 (7.3) 13 (8.6)
Cancer treatment 35 (1.1) 11 (2.8) 7 (2.8) 4 (2.6)
Smoking 193 (7.8) 30 (9.3) 14 (6.9) 16 (13.4)
Computer use >6 h per day 789 (25.4) 124 (31.2) 82 (33.2) 43 (28.5)
Ocular surgery 328 (10.6) 79 (19.8) 38 (15.4) 41 (27.2)
Contact lens wear 310 (10.0) 60 (15.1) 45 (18.2) 15 (9.9)
Antidepressants 257 (8.8) 62 (15.6) 38 (15.4) 24 (15.9)
Anti-Allergy medications 348 (11.2) 83 (20.9) 47 (19.0) 36 (23.8)

+Dry eye was defined as clinical previous dry eye diagnosis or the presence of severe dry eye symptoms.