Skip to main content
. 2017 Sep 12;40(1):87–102. doi: 10.1007/s00281-017-0646-9

Table 3.

Normal plasma concentration of zymogens of coagulation proteases reported to cleave complement components (top section). Normal plasma concentration of complement components reported to be cleaved by coagulation proteases (lower section)

Coagulation zymogen Mw Plasma concentration
kDa mg/L μM
 FXII 100 30 0.3
 FXI 160 5 0.03
 FX 55 10 0.2
 FIX 55 5 0.09
 Prothrombin 72 140 1.9
 Plasminogen 90 130 1.4
Complement component Mw Plasma concentration
kDa mg/L μM
 C1q 400 250 0.6
 C1r 80 50 0.6
 C1s 85 50 0.6
 C4 200 400 2
 C3 185 1500 8
 C2 108 20 0.2
 Factor B 93 200 2.1
 C5 180 80 0.4