Fig. 3.

FHR1, FHR2, and FHR5 have a dimerization motif but lack regulatory domains. Shaded ovals denote regulatory and recognition domains of FH. Percentages shown within ovals of FHR proteins indicate degree of shared homology with corresponding SCR of FH depicted directly above. FHR proteins do not have shared homology with the regulatory domains of FH. However, SCR1 and 2 of FHR1, FHR2, and FHR5 (patterned ovals) have a high degree of shared homology with each other—highlighted in boxed inset. These domains share a dimerization motif