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. 2018 Feb 1;8:2132. doi: 10.1038/s41598-018-19781-5

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Examples of the final PVS segmentation a case of SDS dataset having few PVS. Axial (top row) and sagittal (bottom) slice of T1W, T2W and PVS overlay (red) on T1W. For illustration, T1W is shown in its native space (256 × 256 × 124) and T2W is shown registered to T1W.