Table 1.

Association between the miR-539 expression levels and clinicopathological characteristics of patients with breast cancer.

Variables	Cases	miR-539 expression		P value
		Low (n, %)	High (n, %)
All patients	38	25 (65.8)	13 (34.2)
Age (years)				0.307
$<$45	16	12 (31.6)	4 (10.5)
$\ge 45$	22	13 (34.2)	9 (23.7)
Primary tumor size (cm)				0.732
$\mathrm{<2}$	19	13 (34.2)	6 (15.8)
$\ge 2$	19	12 (31.6)	7 (18.4)
Histological subtype				0.324
Invasive ductal carcinoma	32	20 (52.6)	12 (31.6)
others	6	5 (13.2)	1 (2.6)
AJCC stage				0.653
I-II	28	19 (50.0)	9 (23.7)
III-IV	10	6 (15.8)	4 (10.5)
Histological grade				0.207
G1-G2	20	15 (39.5)	5 (13.2)
G3	18	10 (26.3)	8 (21.1)
Lymph node metastasis				0.009
Negative	21	10 (23.6)	11 (28.9)
Positive	17	15 (39.5)	2 (5.3)
Distant metastasis				0.192
No	33	23 (60.5)	10 (26.3)
Yes	5	2 (5.3)	3 (7.9)
Estrogen receptor				0.510
Negative	12	7 (18.4)	5 (13.2)
Positive	26	18 (47.4)	8 (21.1)

Abbreviations: miR, microRNA; AJCC, American Joint Committee on Cancer.