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. 2017 Dec 12;23(2):177–198. doi: 10.1038/mp.2017.246

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Summary results of systematic search. Size of circle is proportional to the number of identified studies, whereas the colour and position on the graph illustrates the percentage of studies that identified an increase in AD in at least one brain region. AD, Alzheimer’s disease; CD, cluster of differentiation; Iba1, ionized calcium-binding adapter molecule 1; IL, interleukin; MHC, major histocompatibility complex; RCA-1, Ricinus communis agglutin-1; TSPO, translocator protein; TREM2, triggering receptor expressed on myeloid cells 2.