. 2018 Feb 1;8:2194. doi: 10.1038/s41598-018-19854-5

Table 1.

Alteration of chromosomal aberration, micronuclei formation, DNA damage (comet assay), BrdU labelling index and apoptotic index (AI) in bone marrow cells by MUS in CBDCA-treated mice.

Groups	Chromosomal aberrations (CA)		Micronuclei frequency (MN)		DNA damage (comet assay)			BrdU labelling index (BrdU LI)	Apoptotic index (AI)
Groups	% of aberrated cells	% of inhibition	% of micronucleated cells	% of inhibition	Damaged cells (%)	Comet tail length (μm)	Olive tail moment	BrdU labelling index (BrdU LI)	Apoptotic index (AI)
Group 1	7.2 ± 0.6	-------	0.2 ± 0.02	-------	9.7 ± 0.8	14.1 ± 0.7	2.6 ± 0.7	54.1 ± 4.32	0.91 ± 0.07
Group 2	7.1 ± 0.8	-------	0.2 ± 0.01	-------	8.2 ± 0.8	8.9 ± 1.3^*	1.2 ± 0.6^*	55.0 ± 4.4	0.47 ± 0.09
Group 3	41.2 ± 3.4^*	--------	1.7 ± 0.07^*	--------	48.3 ± 3.9^*	31.2 ± 2.3^*	7.3 ± 0.4^*	23.8 ± 1.9^*	53.14 ± 5.1^*
Group 4	32.1 ± 2.9^*	22.0	0.9 ± 0.08^*	46.8	37.1 ± 2.1^*	26.1 ± 0.9^*	4.2 ± 0.6^*	29.7 ± 2.1	49.32 ± 4.7
Group 5	24.3 ± 2.5^*	40.9	0.5 ± 0.06^*	67.6	16.4 ± 1.2^*	16.9 ± 0.4^*	3.4 ± 0.7^*	34.6 ± 3.5^*	21.46 ± 2.8^#
Group 6	18.6 ± 2.7^*	54.8	0.4 ± 0.03^*	76.3	12.4 ± 0.6^*	17.8 ± 1.2^*	3.1 ± 0.5^*	41.3 ± 3.8^*	16.93 ± 2.1^*

Data are represented as mean ± SD, n = 6. *Denotes (P < 0.001), ^#denotes (P < 0.01) as compared to their respective control groups. Comparisons were made between Group 1 with Group 2 and 3; Group 3 with Group 4, 5 and 6.