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. 2018 Feb 1;8:2146. doi: 10.1038/s41598-018-20517-8

Table 2.

Structure of peptides tested in the heterologous receptor functional assay and summary of activity in eliciting a luminescent response.

Peptide Name Peptide Sequence EC50 (nM)a
AedaeACP pQVTFSRDWNAa 10.25
AedaeAKH pQLTFTPSWa NAb
AedaeCRZ pQTFQYSRGWNTNa NAb
AedaeCAPA1 GPTVGLFAFPRVa NAb
AedaeCAPA-PK1 AGNSGANSGMWFGPRLa NAb

aEC50 values are the averages of multiple independent biological replicates involving CHOK1-aeq cells transiently expressing AedaeACPR-I.

bNo activity (NA) detected when tested with peptide titres up to a maximum of 10 µM.