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. 2018 Feb 1;8:2050. doi: 10.1038/s41598-018-20450-w

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Initiation of arrhythmia using a burst pacing protocol for various ATI and F percentages. The left column shows activation maps for the first wave over a timespan of 300 ms. The white lines show the region activated during a time interval of 25 ms (from 75 ms till 100 ms). The gray scale pictures show the distribution of the transmembrane potential at given times t. Movies of all three simulations can be found in the supplementary information.