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. 2018 Jan 10;15(3):2860–2868. doi: 10.3892/etm.2018.5734

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Copyright: © Yan et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 1. — Protein subnetworks of Ras (the query protein) with Raf and ERK1/2. The subnetworks were generated by Cytoscape software. ERK1/2, extracellular signal-regulated kinase 1/2. KRAS, GTPase KRas; BRAF, serine/threonine-protein kinase B-raf; MAP2K, dual specificity mitogen-activated protein kinase kinase; SHOC2, leucine-rich repeat protein SHOC-2; RAF1, RAF proto-oncogene serine/threonine-protein kinase; ARAF, serine/threonine-protein kinase A-Raf; SOS1, son of sevenless homolog 1; RGL2, DELLA protein RGL2.