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. 2018 Jan 4;15(3):2388–2396. doi: 10.3892/etm.2018.5701

Figure 5.

Figure 5.

Effect of eudesmin on H. pylori vacA and cagA expression in and bacterial association to AGS cells. (A) Effect of eudesmin on vacA and cagA mRNA expression in H. pylori 26695-infected AGS cells. H. pylori-infected AGS cells were treated with 0, 10, 20, 40 and 80 µM eudesmin for 6 h. Total mRNA levels of vacA and cagA were determined by reverse transcription-quantitative polymerase chain reaction. aP<0.05 for vacA gene expression vs. non-treatment group. bP<0.05 for cagA gene expression vs. non-treatment group. (B) Effect of eudesmin on H. pylori 26695 association to AGS cells. H. pylori-infected AGS cells were treated with 0, 10, 20, 40 and 80 µM of eudesmin for 6 h. The association ability of H. pylori was determined by bacterial cell counting. Data comparing the eudesmin-treated samples and untreated samples are presented as the mean ± standard deviation in triplicate. aP<0.05 vs. untreated group. H. pylori, Helicobacter pylori.