Table 2.
Examples of ORs-based bioelectronic noses. Adapted from [48].
| Sensor Type | Analytes | Sensitivity | Ref. |
|---|---|---|---|
| Olfactory receptor proteins(ORPs) from bullfrogs (Rana spp.) coated onto the surface of a piezoelectric (PZ) electrode | n-caproic acid, isoamyl acetate, n-decyl alcohol, linalool, ethyl caporate | 10−6–10−7 g | [27] |
| Quartz crystal microbalance (QCM) was coated with ODR-10 receptor (C. elegans) | Diacetyl | - | [28] |
| hOR 2AG1 (hOR2AG1) conjugated carboxylated polypyrrole nanotubes (CPNTs) field-effect transistors (FETs) | Amyl butyrate | 10 fM | [44] |
| Trinitrotoluene (TNT) receptors bound to conjugated polydiacetylene (PDA) polymers with single-walled carbon nanotube field-effect transistors (SWNTFET) | Trinitrotoluene | 1 fM | [49] |
| A liquid-ion gated FET B-nose using human olfactory receptors 2AG1 (hOR2AG1: OR)-conjugated modified bilayer graphene (MBLG) | Amyl butyrate | 0.04 fM | [14] |
| An olfactory-nanovesicle-fused carbon-nanotube-transistor biosensor(OCB) with canine ORs(cfOR5269) | Hexanal | 1 fM | [46] |
| Single-walled carbon nanotube-based FETs (SWNT-FETs) with human OR 2AG1 (hOR2AG1) | Amyl butyrate | 1 fM | [33] |
| Single walled-carbon nanotube field-effect transistors (SWNT-FETs) functionalized with olfactory receptor-derived peptides (ORPs) | Trimethylamine | 10 fM | [34] |
| Nanovesicle-based bioelectronic nose (NvBN) with 30 types of human olfactory receptors (hORs) | Heptanal | 10 fM | [47] |
| Multiplexed superbioelectronic nose (MSB-nose) using graphene micropatterns (GMs) and field-effect transistor (FET) with two different hORs (hOR2AG1 and hOR3A1) | Amyl butylate, helional | 0.1 fM | [13] |
| Olfactory receptor-derived peptides(ORP)-coated Single-walled carbon nanotube-field effect transistors (SWNT-FETs) based on a novel microfluidic system (μBN) | Trimethylamine | 10 ppt | [30] |
| An array of five Surface acoustic wave (SAW) resonators coated with three types of odorant-binding proteins (OBPs): the wild-type OBP from bovine (wtbOBP), a double-mutant of the OBP from bovine (dmbOBP), the wild-type OBP from pig (wtpOBP) | R-(–)-1-octen-3-ol (octenol), R-(–)-carvone (carvone) |
0.48 ppm 0.74 ppm |
[20] |
| Human olfactory receptor (OR) nanovesicle integrated single-walled carbon nanotubes field-effect transistors (SWNT-FETs) | 1-octen-3-ol | 1 fM | [31] |
| Zinc Nanoparticles (NanoZn) equipped biosensor based on olfactory receptor cells bombined with Zinc Nanoparticles (MEA) | Isoamyl acetate, acetic acid | 10−15 M | [50] |