The effects of Vitexin on HIF-1α, VEGF and p38 MAPK protein expression of sevoflurane-induced newborn rat. The effects of Vitexin on (A) HIF-1α, VEGF and p38 MAPK protein expression and (B-D) statistical analysis of sevoflurane-induced newborn rat. Control, control group; Sevoflurane, sevoflurane model group; Vitexin, Vitexin + sevoflurane model group. **P<0.01 compared with the sevoflurane model group; ##P<0.01 compared with the control group.