Table 1.

Transcripts derived from alternative splicing within the E6 open reading frame (ORF). The table summarizes the E6* isoforms for 23 HPV types where alternative splicing has been observed. The detailed donor and acceptor splicing sites for each E6 truncated transcript are enlisted below.

HPV Type	E6* Transcripts	Donor-Acceptor Splicing Sites (Nucleotide Position)	References
16	E6*I	226–409	[59]
	E6*II	226–526	[70]
	E6*III	226–3358	[59]
	E6*IV	226–2709	[71]
	E6*V	221–409	[61]
	E6*VI	191–409	[61]
	E6^E7 (E6*X)	226–742	[60]
	E6^E7*I	174–718	[62]
	E6^E7*II	221–850	[62]
18	E6*I	233–416	[63,64]
	E6*II	233–3434	[63,64]
	E6*III	233–2779	[64]
	E6^E7	233–791	[60,64]
26	E6*I	173–406	[21]
30	E6*I	229–420	[21]
31	E6*I	210–413	[65,68]
	E6^E4 (E6*III)	210–3295	[65]
33	E6*I	231–509	[66]
	E6*II	231–785	[66]
	E6*III	231–3351	[66]
34	E6*I	223–414	[21]
35	E6*I	228–419	[21]
39	E6*I	231–420	[21]
45	E6*I	230–413	[69]
51	E6*I	173–406	[21]
52	E6*I	224–502	[69]
53	E6*I	236–419	[69]
56	E6*I	157–420	[21]
58	E6*I	232–510	[67]
	E6*II	232–3355	[67]
59	E6*I	183–582	[69]
66	E6*I	157–420	[21]
67	E6*I	224–502	[69]
68b	E6*I	232–415	[69]
69	E6*I	178–411	[21]
70	E6*I	231–422	[21]
73	E6*I	227–410	[69]
82	E6*I	178–411	[21]