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. 2018 Jan 22;10(1):49. doi: 10.3390/v10010049

Figure 7.

Figure 7

Pathogenic manifestations of PRVABC59 infection in the 1-day-old C57BL/6 mice. The PRVABC59-infected 1-day-old mice were closely observed and typical symptoms were recorded. Representative images at 11 dpi presented as: (A) Hind-limb paralysis a; (B) PBS-injected mouse control; (C) (upper versus lower). PBS-injected control mouse versus wasting and paralysis; (D) form an arch on back; (E) Symptoms, morbidity rate, and onset date of PRVABC59-infected mice; (F) The averaged body weight of ZIKV-infected or PBS-injected Mice (n = 8–10 per group); (G) Whole brain sizes; (H) Brain weights. The averaged brain weight from ZIKV-infected or PBS-injected mice at 3, 6, 9, or 11 dpi (n = 3). * p < 0.05, the averaged brain weight from ZIKV-infected mice at 9 dpi was compared to that at 11 dpi. # p < 0.05, the averaged brain weight from ZIKV-infected mice was compared with that of PBS-injected mice at 11 dpi, all data are means ± S.D., t-test.