Figure 1.

Pro-inflammatory milieu induced by coculturing of human lung cancer A427 cell line and human monocytic AML-193 cell line. A427 cells were cultured along with AML-193 at ratios of 1:1, 1:10, 1:15, 1:25 and 1:50. The 1:15 ratio produced a high inflammatory response. When cultured alone, neither of the cell lines were able to produce an inflammatory response for (A) TNF-α and (B) IL-6. Data are represented as mean + standard deviation. of three independent experiments. *P<0.05, **P<0.01 vs. A427. TNF, tumor necrosis factor; IL, interleukin.