HDAC2 immunohistochemistry. Lung tissue slices from each treatment group were immunostained for HDAC2. Magnification, ×200. (A) Control, (B) COPD, (C) budesonide, (D) TCHM + budesonide and (E) theophylline + budesonide groups. One representative image from each group is shown (n=8). HDAC2, histone deacetylase 2; COPD, chronic obstructive pulmonary disease; TCHM, traditional Chinese herbal medicine.