The effect of H2O2 administration on NP cells. (A) The expression of COL2 and TSHZ3 and (B) miR-125b-1-3p were determined in NP cells following treatment with 0.5, 1.0 and 1.5 mM/l H2O2 for 24 h. **P<0.01 vs. control cells. miR, microRNA. NP, nucleus pulposus; TSHZ3, Teashirt zinc finger homeobox 3; COL2, collagenase type II.