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Downregulation of Fbxw7 increases the migration and invasion of 786-O cells in vitro. The effect of Fbxw7 siRNA interference on Fbxw7 expression in 786-O cells was confirmed by western blot analysis. **P<0.01 with comparisons shown by lines. Fbxw7, F-box and WD repeat domain containing 7; NC, negative control; siRNA, small interfering RNA.
