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. 2018 Jan 8;15(3):3694–3702. doi: 10.3892/ol.2018.7744

Table I.

Association of Fbxw7 expression with clinicopathological factors in 70 patients with renal cell carcinoma.

Fbxw7 expression

Patient clinicopathological parameters Number of cases Low expression High expression P-values
Age (years) 0.994
  ≤60 33   8 25
  >60 37   9 28
Sex 0.306
  Male 42 12 30
  Female 28   5 23
Histological grade 0.262
  Well 45   9 36
  Moderate and poor 25   8 17
Tumor size 0.856
  ≤5 cm 44 11 33
  >5 cm 26   6 20
Tumor stage 0.005a
  I and II 41   5 36
  III and IV 29 12 17
Lymph node metastasis 0.003a
  Positive 21 10 11
  Negative 49   7 42
Distant metastasis 0.006a
  Positive 12   7   5
  Negative 58 10 48
a

P<0.05. Fbxw7, F-box and WD repeat domain containing 7.