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. 2018 Feb 2;18:48. doi: 10.1186/s12906-018-2116-x

Table 11.

Binding affinities (kJ/mol) and in vitro inhibitory activity (IC50) of different PLA2 inhibitors

Compound name IC50 (μM) [8688] Binding affinity
(kJ/mol)
LY 311727 < 1 −39.75
Manoalide 16 −39.33
Indomethacin 35 −36.82
Manoalogue 26 −34.31
Aristolochic Acid 40 −33.89
1,1,1-Trifluoro-2-heptadecanone 45 −27.20