Isodose curves of IMRT plan and 2PA-VMAT plan in peripheral lung cancer. (A) Isodose curves of IMRT plan. (B) Isodose curves of SA-VMAT plan. (C) Isodose curves of PA-VMAT plan. (D) Isodose curves of 2PA-VMAT plan. In peripheral lung cancer, both IMRT plan and VMAT plan exhibited satisfying prescribed tumor target coverage and OAR sparing. However, 2PA-VMAT displayed improved PTV coverage compared with IMRT. 2PA-VMAT exhibited better sparing of spinal cord, lung-all, and lung-contralateral compared with IMRT, while IMRT exhibited better heart and lung-ipsilateral sparing compared with 2PA-VMAT. IMRT had better dose conformity and homogeneity. IMRT, intensity-modulated radiation therapy; VMAT, volumetric modulated arc therapy; 2PA, double partial arc; PA, partial arc; SA, single arc; OAR, organs-at-risk.