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Antibody-dependent enhancement of pE60 variants. Serial dilutions of E60 variants were mixed with DENV-2 and added to FcγR-expressing K562 cells. Forty-eight hours later, cells were fixed, permeabilized and stained with anti-DENV E antibody 4G2 and analyzed by flow cytometry for DENV infection of cells. (From [104] with permission from JGV).
