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. 2017 Dec 26;19(1):61. doi: 10.3390/ijms19010061

Figure 1.

Figure 1

Schematic illustration of sexual dimorphism pathways after neonatal ischemia and hypoxia-ischemia. Major molecular pathways, including the lesion size and behavioral deficits (middle column), in male (blue, left column) and female (pink, right column), with relative agreements in the literature. In black, lack of consensus in the literature and/or single report. AIF: apoptosis inducing factor; eNOS: endothelial nitric oxide synthase; nNOS: neuronal NOS; iNO: inhaled NO; ROS: reactive oxygen species.