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. 2017 Dec 28;19(1):72. doi: 10.3390/ijms19010072

Figure 4.

Figure 4

A sliding window analysis of the AK gene family exhibits the twelve kinase subdomains. A ten amino acid sliding window was employed to determine dN (blue), dS (green) and dN/dS (red) value for (A) the entire AK gene, (B) AKA, (C) AKB, and (D) AKC. Values were plotted at the center of each window. Dashed lines demarcate the kinase domain. The bars highlight motifs, including the N-terminal lobe; the hinge; the C-terminal lobe; the activation loop; the KEN-, A-, and D-boxes; and the twelve kinase subdomains (I–XI).