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. 2017 Dec 28;19(1):81. doi: 10.3390/ijms19010081

Table 2.

Antiproliferative activities of the tested monoterpene analogs.

Analog Conc. (µM) Inhibition (%) ± SEM [Calculated IC50 Value (µM)]
HeLa A2780 MCF7 MDA-MB-231
3 10 29.83 ± 1.65 96.66 ± 0.23 35.07 ± 2.64 19.06 ± 2.98
30 98.46 ± 0.08 96.60 ± 0.37 93.00 ± 0.68 84.58 ± 1.87
[12.23] [1.44] [12.37] [16.47]
4 10 37.96 ± 2.20 96.28 ± 0.32 49.99 ± 0.80 33.33 ± 1.94
30 98.17 ± 0.19 96.82 ± 0.18 96.08 ± 0.52 89.95 ± 0.90
[11.46] [1.91] [10.02] [13.02]
5 10 21.94 ± 2.94 91.95 ± 0.26 28.62 ± 1.98 20.31 ± 1.45
30 96.31 ± 0.33 93.77 ± 0.27 85.27 ± 1.84 58.06 ± 1.75
[13.62] [2.05] [14.54] [24.28]
6 10 – * 56.80 ± 3.18 17.30 ± 1.74 19.61 ± 2.23
30 47.39 ± 2.99 93.34 ± 0.69 23.87 ± 2.37 29.68 ± 2.54
7 10 15.35 ± 1.79 19.80 ± 1.99
30 24.18 ± 2.42 36.92 ± 1.39 23.44 ± 1.86 24.66 ± 1.38
8 10 12.18 ± 1.70 14.62 ± 2.49 11.71 ± 0.74
30 12.31 ± 2.25 36.58 ± 1.38 35.75 ± 2.79 20.27 ± 2.62
9 10 11.45 ± 2.75
30 10.83 ± 2.40 34.56 ± 1.83 21.57 ± 1.69
10 10 17.93 ± 1.06 11.43 ± 1.68
30 26.01 ± 0.74 48.27 ± 0.64 44.00 ± 1.34 24.67 ± 2.13
11 10 12.36 ± 1.23
30 13.41 ± 1.87 28.44 ± 0.92 25.32 ± 1.10 10.36 ± 2.14
12 10 15.51 ± 2.77
30 31.13 ± 2.48 15.92 ± 2.69
13 10 11.76 ± 0.76
30 48.66 ± 1.97 18.81 ± 2.59
14 10
30 29.12 ± 2.32 14.46 ± 2.31 16.28 ± 1.85
cisplatin 10 42.61 ± 2.33 83.57 ± 1.21 53.03 ± 2.29 67.51 ± 1.01
30 99.93 ± 0.26 95.02 ± 0.28 86.90 ± 1.24 87.75 ± 1.10
[12.43] [1.30] [5.78] [3.74]

* Growth inhibition values less than 10% are considered negligible and not given numerically.