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Assessment of diarrhea parameters after CPT-11 administration. CPT-11 (100 mg/kg/day) was administered in rats via the tail vein for 4 days. The total weight of fecal pellets (A), total number of fecal pellets (B), and fecal water content (C) were measured on the third day following the last administration. The fecal water content is shown with the mean value of the control group set at 100% (mean ± SD, n = 8, Student’s t-test: * p < 0.05, *** p < 0.001 vs. Cont.).
