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. 2018 Jan 6;19(1):172. doi: 10.3390/ijms19010172

Figure 2.

Figure 2

Western blots analyses of the H3 and H4 acetylation levels in nuclear extracts from OGD-exposed cortical neurons treated for 2 h with valproate (VPA) alone or in combination with resveratrol. (A,B) VPA (1 nmol/mL) did not increase per se the amount of H3 (K9/18) and H4 (K16) acetylation. Treatment with combined VPA (1 nmol/mL) and resveratrol (3 nmol/mL) completely restored the histone H3 acetylation. In the densitometry analysis of immunoblot bands data were expressed as percentage of the corresponding control value. Bars depicted the mean ± s.e.m. of three separate experiments, * p < 0.05 and ** p < 0.01 versus the corresponding OGD value.