Figure 4.

The PCA treatment reduces seizure-induced neuronal loss. Live neurons were detected by neuronal nuclear (NeuN) antigen immunohistochemical staining. Animals were either seizure-vehicle-treated or PCA-treated after a seizure. (A) is a representative image of the NeuN staining in the hippocampus and in the enlarged view of the CA1, CA3, hilus, and sub. Scale bar = 100 μm. (B) is a series of bar graphs indicating the number of NeuN⁺ neurons in the hippocampus after a seizure. When compared to the seizure-vehicle-treated group, the PCA-treated group had a higher number of NeuN⁺ neurons. Data: mean ± SEM, n = 5–7 from each group, * p < 0.05. The hilus is not statistically significant.