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. 2018 Jan 8;19(1):187. doi: 10.3390/ijms19010187

Figure 5.

Figure 5

PCA treatment reduces microglia activation. Seizure-induced microglia activation was reduced by PCA treatment. Microglia activation was evaluated by CD11b staining. (A) shows microglia activation in CA1 of the hippocampus. One week after the seizure, microglia activation had occurred in the seizure group. In the CA1 area of the hippocampus, the PCA treatment reduced microglia activation when compared to the vehicle-treated group. Scale bar = 100 μm. (B) shows quantitated microglia activation in the hippocampus. (C) Iba1 and CD68 immunoreactive cells were expressed in the hippocampus. Iba1 and CD68 activation had occurred in the seizure group. The activities of Iba1 and CD68 were decreased in the PCA-treated group. Data: mean ± SEM, n = 5–7 from each group, * p < 0.05.