Table 4.
Relative mRNA expression of longevity-associated genes in male and female w1118 D. melanogaster in dependence of resveratrol (RESV; 500 µmol/L) administration for ten days compared to controls.
| Sex | Transcript | |||||
|---|---|---|---|---|---|---|
| Sir2 1 | p-Value 4 | INDY 2 | p-Value 4 | Srl 3 | p-Value 4 | |
| Male | 0.90 ± 0.19 | 0.700 | 1.13 ± 0.15 | 0.437 | 1.77 ± 0.74 | 0.375 |
| Female | 0.83 ± 0.12 | 0.405 | 1.02 ± 0.14 | 0.913 | 1.12 ± 0.19 | 0.593 |
Data are shown as means ± SEM comprising 40 flies/group in total from two independent experiments; α-Tubulin at 84B (αTub84B) and Ribosomal protein L32 (RpL32) served as the housekeeping genes. Statistics: 2-sided Student’s t-test and Mann–Whitney U. 1 Sir2: Sirtuin 2; 2 INDY: I’m Not Dead Yet; 3 srl: spargel; 4 p-value indicates differences in relative mRNA expression in whole body RNA extracts of resveratrol-treated flies compared to controls.