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. 2018 Jan 11;19(1):225. doi: 10.3390/ijms19010225

Figure 6.

Figure 6

Osteogenesis-related gene expression after dioxin and AhR antagonist co-treatment. (A) CYP1A1 protein levels returned to near-baseline levels with AhR antagonist co-treatment. * p < 0.05 relative to 100 nM dioxin condition; (B) CXCL12 mRNA expression was recovered by co-treatment with AhR antagonists. CXCR4 mRNA expression was restored to control levels or higher by co-treatment with resveratrol and 3,3′-diindolylmethane (DIM). ALP and RUNX2 mRNA expression was recovered by AhR antagonist co-treatment. * p < 0.05 relative to 100 nM dioxin condition, ^ p < 0.05 relative to 0 nM dioxin condition. Error bar means ± SEM.