Table 3.

Performance of survivin, UBC^® Rapid, and combination based on single-marker cut-off for the detection of bladder cancer.

Groups	Cut-Off	Sensitivity (%)	Specificity (%)	True-Positive (n)	True-Negative (n)	False-Positive (n)	False-Negative (n)
Survivin ELISA
Tumor vs. Controls	0.033 ng/mL	35	98	39	131	2	72
High-grade tumor vs. Controls		51	98	28	131	2	27
Low-grade tumor vs. Controls		18	98	10	131	2	45
UBC®Rapid
Tumor vs. Controls	10.0 mg/L	56	96	62	128	5	49
High-grade tumor vs. Controls		73	96	40	128	5	15
Low-grade tumor vs. Controls		40	96	22	128	5	33
Combination
Tumor vs. Controls	>Survivin or >UBC® Rapid	66	95	73	127	6	38
High-grade tumor vs. Controls		82	95	45	127	6	10
Low-grade tumor vs. Controls		49	95	27	127	6	28