Table 1.

Summary of in vivo studies associating mast cells (MCs) with cardiac fibrosis.

Species	Model/Pathology	Outcome	Heart Chamber	References
Human	Fibrosis	↑ MC	LV	[13,14]
Rat	Pulmonary hypertension	↑ MC	RV	[6]
Human	Transplantation	MC number correlated with fibrosis	LV	[8]
Mouse	Myocarditis	↑ histamine, ↑ MC correlated with fibrosis	LV	[15,19]
Rat	Hypertension	↑ MC correlated with fibrosis	LV	[5]
Mouse	Pulmonary hypertension	↑ MC	RV	[21]

LV = Left ventricle, RV = Right ventricle.