Figure 5.

Retrobulbar lidocaine is neuroprotective in early DBA/2J glaucoma. (A,B) examples of confocal images of RBPMS-positive RGCs in whole-mounted retinas of one nine-month-old D2 that received four retrobulbar injections of lidocaine at four months of age in one eye (B) and an equal volume of PBS in the other eye (A), scale bar, 50 µm; (C) Mean RGC density in D2 mice nine mo. old treated with retrobulbar lidocaine in one eye and PBS in the contralateral eye at four months of age. RGC density is higher in lidocaine-treated eyes by 35% (p = 0.04). Error bars represent the SEM, N = 6. Black dots represent measurements in individual mice.