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. 2018 Jan 15;19(1):254. doi: 10.3390/ijms19010254

Figure 2.

Figure 2

Figure 2

Effect of GA on the expression of insulin signal transduction-related proteins (A) insulin receptor (IR) and GLUT4, and (B) PKC-ζ in adipose tissues of HFD rats. GA: gallic acid; IR: insulin receptor; GLUT4: glucose transporter 4; PKC-ζ: protein kinase C-zeta; Normal: rats fed a normal diet; HFD: rats fed a 66% fructose diet; HFD + Pio (30): rats fed a 66% fructose diet and orally administered pioglitazone (30 mg/kg body weight); HFD + GA (30): rats fed a 66% fructose diet and orally administered GA (30 mg/kg body weight); HFD + GA (10): rats fed a 66% fructose diet and orally administered GA (10 mg/kg body weight). Different letters (a–c) indicate a significant difference at p < 0.05. Values calculated as the means ± SD for six rats in each group. The relative expressions of IR, GLUT4, and PKC-ζ in each treatment group were calculated using α-tublin as the standard.