5-FU	5-fluorouracil
A2780	human ovarian carcinoma cell line
ABCB1	ATP binding cassette subfamily B member 1
ABCC10	ATP binding cassette subfamily C member 10
Akt	serine/threonine-specific protein kinase
b.w.	body weight
Bak	pro-apoptotic Bcl-2 protein
Bax	bcl-2-like protein 4
Bcl-2	B-cell lymphoma 2 protein
BCR-ABL1	breakpoint cluster region protein-Abelson murine leukemia viral oncogene homolog 1
CDKI	cyclin-dependent kinase inhibitors
colon 205	human Caucasian colon adenocarcinoma cell line
CoMFA	comparative molecular field analysis
CoMSIA	comparative molecular similarity index analysis
CYP	cytochrome P450
DNA	deoxyribonucleic acid
EMA	European Medicines Agency
ERK	extracellular signal-regulated kinases
FAO	Food And Agriculture Organization
FDA	Food And Drug Administration
FGF	fibroblast growth factor
FLT3-ITD	fms-related tyrosine kinase 3 internal tandem duplication
HIF-1α	hypoxia-inducible factor 1-alpha
HMGB1	high mobility group box 1 protein
IC50	half maximal inhibitory concentration
MAPK	mitogen-activated protein kinase
Mcl-1	induced myeloid leukemia cell differentiation protein
MDR	multidrug resistance
miRNA	micro-ribonucleic acid
MMP	matrix metalloproteinase
mRNA	messenger ribonucleic acid
Myc	proto-oncogene
nab-paclitaxel	nanoparticle albumin-bound paclitaxel
NF-κB	nuclear factor kappa B cells
Nrf2	nuclear factor (erythroid-derived 2)-like 2
P-388	bipotential murine pre-B cell lymphoma
PEP005	ingenol mebutate
PGDF	platelet-derived growth factor
P-gp	p-glycoprotein
PI3K	phosphatidylinositol-4,5-bisphosphate 3-kinase
PICN	paclitaxel injection concentrate for nanodispersion
PKC	protein kinase C
PKCα	protein kinase C-α
PKCδ	protein kinase C-δ
QSAR	quantitative structure activity relationship
RAID	rapid access to intervention in development
SAR	structure activity relationship
SCD-1	stearoyl-CoA- desaturase 1
SCLC	small-cell lung cancer
SIRT1	NAD-dependent protein deacetylase sirtuin-1
SM/Chol	sphingomyelin/cholesterol
smad3	mothers against decapentaplegic homolog 3
Sp1	specificity protein 1
STAT3	signal transducer and activator of transcription 3
T315I	mutation resulting in an amino acid substitution at position 315 in BCR-ABL1, from a threonine (T) to an isoleucine (I).
TGF-β	transforming growth factor beta
TRAIL	tumor necrosis factor-related apoptosis-inducing ligand
tRNA	transfer ribonucleic acid
uPAR	urokinase receptor
VEGF	vascular endothelial growth factor
WHO	World Health Organization