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Synthetic Lipid-metabolites partially inhibit T cell proliferation. In total, 50,000 control PBLs from healthy donors were stimulated with αCD3/28 for three days in the presence of 9(R)HODE, 9(S)HODE or 13-OxODE. Only 9(R)HODE decreased the proliferation of control PBLs. Data given as mean of cpm 3HTdR incorporation of triplicate cultures ± SEM. Statistical analysis was performed using one-way ANOVA with Bonferroni post-test (*** p < 0.001).
