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. 2018 Jan 17;19(1):274. doi: 10.3390/ijms19010274

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© 2018 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Quantification of total Telomeric Repeat-Containing RNA (TERRA) levels by slot blot hybridization in 23 head and neck squamous cell carcinoma (HNSCC) patients. Tumor samples (red bars), samples from metastatic tissue (green bars) and samples from adjacent nontumoral tissue (blue bars). For each patient, the value of the normal tissue has been set to 1. In group (A), the value in the tumor sample was either similar to the value in the healthy tissue (p > 0.05) (patients 9, 35, 38, 2, 37, 28, 14, 3) or was significantly higher (p < 0.05) (patients 22, 20, 7, 18, 21, 17). In group (B), the value in the tumor was significantly lower (p < 0.05) than in the healthy tissue.