Figure 2.

Telomere-specific TERRA levels by qRT-PCR (quantitative Real Time-Polymerase Chain Reaction) in 5 HNSCC patients. Quantitative RT-PCR experiments were carried out to measure of TERRA expression from 10q, 15q, XpYp and XqYq telomeres. Tumor samples (red bars) and samples from adjacent nontumoral tissue (blue bars). For each patient, TERRA expression level in the normal tissue is set to 1 and used as reference. For each sample, three replicates were amplified. (A) Patients with higher or similar TERRA levels in tumor compared to normal tissue; (B) Patients with lower TERRA levels in tumor compared to normal tissue.