Table 3.
Results of univariate log-rank analysis of prognostic factors for overall survival (OS) and disease-free survival (DFS) in 106 patients with ESCC receiving esophagectomy.
| Factors | No. of Patients | Overall Survival (OS) | Disease-Free Survival (DFS) | ||
|---|---|---|---|---|---|
| 5-year OS (%) | p Value | 5-year DFS (%) | p Value | ||
| Age (years) | |||||
| <55 | 52 | 56% | 0.32 | 52% | 0.17 |
| ≥55 | 54 | 41% | 33% | ||
| Location | |||||
| U + M | 55 | 55% | 0.20 | 46% | 0.42 |
| L | 51 | 41% | 39% | ||
| T classification | |||||
| T1 + 2 | 70 | 56% | 0.013 * | 49% | 0.022 * |
| T3 + 4 | 36 | 33% | 31% | ||
| N classification | |||||
| N0 | 70 | 63% | <0.001 * | 54% | <0.001 * |
| N1 + 2 + 3 | 36 | 19% | 19% | ||
| 7th AJCC stage | |||||
| I | 38 | 63% | 0.008 * | 58% | 0.002 * |
| II + III + IV | 68 | 40% | 34% | ||
| Histological grading | |||||
| Grade 1 + 2 | 80 | 50% | 0.33 | 43% | 0.62 |
| Grade 3 | 26 | 42% | 42% | ||
| Surgical margin | |||||
| Negative | 91 | 52% | 0.015 * | 45% | 0.11 |
| Positive | 15 | 27% | 27% | ||
| UTX expression | |||||
| Low expression | 62 | 39% | 0.011 * | 32% | 0.01 * |
| High expression | 44 | 61% | 57% | ||
| E-cadherin expression | |||||
| Low expression | 50 | 38% | 0.026 * | 28% | 0.005 * |
| High expression | 56 | 57% | 55% | ||
| Low UTX/E-cadherin expression | |||||
| Presence | 36 | 31% | 0.001 * | 22% | <0.001 * |
| Absence | 70 | 57% | 53% | ||
AJCC, American Joint Committee on Cancer. * Statistically significant.