Table 4.
Multivariate analysis of PFS and OS.
| Baseline | PFS | OS | ||
|---|---|---|---|---|
| HR (95% CI) | p | HR (95% CI) | p | |
| has-miR-20b-5p | 0.922 (0.847–0.989) | 0.035 | 0.930 (0.850–0.995) | 0.046 |
| has-miR-29b-3p | 0.854 (0.728–0.997) | 0.045 | 0.872 (0.753–0.991) | 0.039 |
| has-miR-424-5p | 0.968 (0.877–1.069) | 0.517 | 0.936 (0.838–1.046) | 0.242 |
| has-miR-155-5p | 0.927 (0.863–0.997) | 0.040 | 0.917 (0.850–0.990) | 0.026 |
| ECOG PS (1–2 vs. 0) | 1.206 (0.424–3.433) | 0.725 | 1.838 (0.667–5.060) | 0.239 |
| BRAF (mutated vs. wild type) | 3.574 (1.075–11.882) | 0.038 | 3.628 (1.063–12.378) | 0.040 |
| Age, years (≥65 vs. <65) | 2.207 (0.987–4.935) | 0.054 | 1.478 (0.650–3.364) | 0.351 |