7-TM	7-transmembrane
APC	adenomatous polyposis coli
CK1	casein kinase 1
CRD	cysteine-rich domain
EMT	epithelial-to-mesenchymal transition
FZD	Frizzled
GPCRs	G-protein coupled receptors
GSK3β GDP GTP	glycogen synthase kinase 3β Guanosine disphosphate Guanosine triphosphate
HCC	hepatocellular carcinoma
HBV	hepatitis B virus
HBx	hepatitis B X protein
HCV	hepatitis C virus
JNK	c-Jun N-terminal protein kinase
LRP 5/6	LDL receptor-related proteins 5 and 6
LEF/TCF	lymphoid enhancer factor/T cell factor
ROCK	Rho-associated kinase
T-ICs	tumor-initiating cells
SAPK	stress-activated protein kinase
sFRP	secreted frizzled-related protein
PCP	Planar cell polarity
PDZ	Psd-95/Disc large/ZO-1 homologous