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. 2018 Jan 22;19(1):320. doi: 10.3390/ijms19010320

Figure 3.

Figure 3

The location of 16 amyloidogenic FGA variants. All amyloidogenic variants crowd in a quite limited portion from residue 517 to 555 of the mature Aα-chain. In eight frameshift variants, the C-terminal sequences resulted from frameshift variants (red italic letters) bear a close resemblance to each other, and the C-terminal peptides consisting of 24 amino acids (underline) are identical.