Table II.
Association between rs16900627 polymorphisms and gastric cancer.
| A, G allele carriers vs. the others | |||||
|---|---|---|---|---|---|
| rs16900627a | AA | AG | GG | AG+GG vs. AA, OR (95% CI) | P-value |
| Non-GC (697) | 554 | 130 | 13 | Reference | |
| Overall GC (524) | 395 | 115 | 14 | 1.38 (1.03–1.84) | 0.032 |
| Intestinal (309) | 227 | 74 | 8 | 1.56 (1.11–2.20) | 0.011 |
| Diffuse (212) | 166 | 40 | 6 | 1.15 (0.778–1.69) | 0.491 |
| Unknown | 2 | 1 | 0 | – | – |
| B, Co-variable: The number of G allele | |||||
| rs16900627a | AA | AG | GG | No. of G allele, OR (95% CI) | P-value |
| Non-GC (697) | 554 | 130 | 13 | Reference | |
| Overall GC (524) | 395 | 115 | 14 | 1.37 (1.06–1.77) | 0.016 |
| Intestinal (309) | 227 | 74 | 8 | 1.53 (1.13–2.07) | 0.006 |
| Diffuse (212) | 166 | 40 | 6 | 1.20 (0.857–1.68) | 0.288 |
| Unknown | 2 | 1 | 0 | – | – |
a
The number of subjects following logistic regression analysis after adjustment for age, gender and H. pylori infection status. CI, confidence interval; GC, gastric cancer; OR, odds ratio.