Table 2.
Comparison of performances of DNA electrochemical sensors for total antioxidant capacity.
| Sample | Target Layer | Free Radical | Linear Range | LOD | Advantages/Disadvantages | Ref. |
|---|---|---|---|---|---|---|
| Flavoured water containing ascorbic acid | Adenine Guanine | Hydroxyl radical | 2–18 mg L−1 0.5–5 mg L−1 |
0.1 mg L−1 0.08 mg L−1 |
Advantage: -Reproducibility, constant sensitivity and avoidance of sample contamination, rapid and inexpensive evaluation of antioxidant capacity |
[39] |
| Ascorbic acid | dsDNA | Hydroxyl radical | 1.5–2.5 mmol·L−1 | 0.82 mmol·L−1 | Disadvantage: -Narrow concentration range |
[40] |
| Beverages | dA21 | Hydroxyl radical | 0.05–1.00 µmol·L−1 | 50 nmol·L−1 | Advantage: -Easy, rapid, reproducible preparation, low detectability, TAC evaluation |
[31] |
| Fruit flavoured water beverage | Guanine Adenine | Superoxide radical | 1–5 mg L−1 0.5–4 mg L−1 |
0.77 mg L−1 0.5 mg L−1 |
Advantage: -Shorter detection time, smaller sample volume, higher accuracy, high simplicity and can be use without pretreatment |
[35] |
| Fruit flavoured water beverage | Guanine Adenine | Sulfate radical | 0.5–4 mg L−1 0.5–4 mg L−1 |
0.47 mg L−1 0.5 mg L−1 |
Advantage: Ease of preparation, rapid, reproducible. Disadvantage: Disposable |
[45] |
| Orange-based beverages containing ascorbic acid | dA20-CPE | Nitric oxide radical | 1–20 mg L−1 | 0.23 mg L−1 | Advantage: -Inexpensive simple, stable and short response time |
[46] |
| Pharm. antioxidant excipient in drugs (Na2S2O5) | Guanine | Hydroxyl radical | 1–30 mmol·L−1 | 0.54 mmol·L−1 | Advantage: -The surface area of Guanine/TiO2 NPs/MWCNTs/GCE has a large surface area and good electrochemical properties |
[47] |