Table II.
DNA repair proteins | ||||||||
---|---|---|---|---|---|---|---|---|
Gene | Analysis | Tumor size (mm) | MLH1 | MSH2 | MSH6 | PMS2 | MGMT | ERCC1 |
CDX2 | Correlation coefficient | −0.247a | 0.388b | 0.334b | 0.317b | 0.228a | 0.236a | 0.574b |
Significance (2-sided) | 0.038 | <0.001 | 0.002 | 0.004 | 0.040 | 0.039 | <0.001 | |
Number of valid cases | 71 | 77 | 82 | 82 | 82 | 77 | 74 |
P<0.05
P<0.01. CDX2, caudal type homeobox 2; MLH1, MutL Homolog 1; MSH, MutS protein Homolog; PMS2, postmeiotic segregation increased 2; MGMT, O6-methylguanine DNA methyltransferase; ERCC1, excision repair cross-complementing 1.