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. 2018 Feb 1;19:30. doi: 10.1186/s12859-018-2041-5

Fig. 3.

Fig. 3

Workflow of using JSON-LD and BioThings API Registry to perform complex queries. By combining JSON-LD and BioThings API Registry, the Python function IdListHandler is able to select the API which is able to perform the task and automatically executes the queries to return the desired output. Users could easily get a list of drug candidates related to a rare Mendelian disease by the following path: HGVS ID → NCBI Gene ID → WikiPathways ID → NCBI Gene ID → UniProt ID → Drug InChI Key. It only requires the user to specify the input/output type at each step